Analysis by high density cDNA arrays of altered gene expression in human intestinal epithelial cells in response to infection with the invasive enteric bacteria Salmonella.

@article{Eckmann2000AnalysisBH,
  title={Analysis by high density cDNA arrays of altered gene expression in human intestinal epithelial cells in response to infection with the invasive enteric bacteria Salmonella.},
  author={Lars Eckmann and James R. Smith and Michael P. Housley and Michael B. Dwinell and Martin F. Kagnoff},
  journal={The Journal of biological chemistry},
  year={2000},
  volume={275 19},
  pages={14084-94}
}
Many clinically important enteric pathogens initiate disease by invading and passing through the intestinal epithelium, a process accompanied by increased epithelial expression of proinflammatory cytokines. To further define the role intestinal epithelial cells play in initiating and modulating the host response to infection with invasive bacteria, hybrid selection on high density cDNA arrays was used to characterize the mRNA expression profile of approximately 4,300 genes in human intestinal… CONTINUE READING