Analysis and pharmacokinetics of glycyrrhizic acid and glycyrrhetinic acid in humans and experimental animals

@article{Krhenbhl1994AnalysisAP,
  title={Analysis and pharmacokinetics of glycyrrhizic acid and glycyrrhetinic acid in humans and experimental animals},
  author={S. Kr{\"a}henb{\"u}hl and F. Hasler and R. Krapf},
  journal={Steroids},
  year={1994},
  volume={59},
  pages={121-126}
}
  • S. Krähenbühl, F. Hasler, R. Krapf
  • Published 1994
  • Chemistry, Medicine
  • Steroids
  • Glycyrrhizic acid (GZA) and glycyrrhetinic acid (GRA) can be determined rapidly and precisely by high-performance liquid chromatography (HPLC) in biological fluids and tissues from experimental animals and humans. From plasma and tissues, GZA and GRA are extracted by organic solvents and the extracts can directly be used for HPLC. From bile or urine, extraction and determination of GZA and GRA are more difficult due to interfering endogenous compounds and conjugation of GRA with glucuronides or… CONTINUE READING
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