Analysis and evaluation of trans,trans-muconic acid as a biomarker for benzene exposure.

  title={Analysis and evaluation of trans,trans-muconic acid as a biomarker for benzene exposure.},
  author={Gerhard Scherer and Thomas Renner and Michael Meger},
  journal={Journal of chromatography. B, Biomedical sciences and applications},
  volume={717 1-2},
Benzene is an important industrial chemical and, due to its occurrence in mineral oil and its formation in many combustion processes, a widespread environmental pollutant. Since benzene is hematoxic and has been classified as a human carcinogen, monitoring and control of benzene exposure is of importance. Although trans,trans-muconic acid (ttMA) was identified as a urinary metabolite of benzene at the beginning of this century, only recently has its application as a biomarker for occupational… CONTINUE READING
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