Analyses of Stemona alkaloids in Stemona tuberosa by liquid chromatography/tandem mass spectrometry.

@article{Zhou2006AnalysesOS,
  title={Analyses of Stemona alkaloids in Stemona tuberosa by liquid chromatography/tandem mass spectrometry.},
  author={Yan Zhou and Ren‐Wang Jiang and Po Ming Hon and Yan-tong Xu and Yiu-Man Chan and Tak Wah Dominic Chan and Hong-Xi Xu and Li-Sheng Ding and Paul Pui-Hay But and Pang-Chui Shaw},
  journal={Rapid communications in mass spectrometry : RCM},
  year={2006},
  volume={20 6},
  pages={
          1030-8
        }
}
  • Yan Zhou, R. Jiang, P. Shaw
  • Published 30 March 2006
  • Chemistry
  • Rapid communications in mass spectrometry : RCM
Alkaloid profiles in Stemona tuberosa were found to be highly variable. Six Stemona alkaloids isolated from the plant were subjected to on-line high-performance liquid chromatography/electrospray ionization mass spectrometry (HPLC/ESI-MS) and tandem mass spectrometry (MS/MS) analyses. Their fragmentation patterns and products were useful for their characterization. The LC/MS fingerprints of these alkaloids, though variable among samples, could provide an overall characterization of the… 
Identification of structurally diverse alkaloids in Corydalis species by liquid chromatography/electrospray ionization tandem mass spectrometry.
TLDR
The LC/ESI-MS/MS technique was effective in obtaining structural information and yielded diagnostic ions for diverse alkaloids and marker compounds were suggested for the three C. species with different geographic origins.
Two New Alkaloids from Stemona tuberosa
Two new alkaloids, named tuberostemoninol A (1) and tuberostemoninol B (2), along with the known compounds tuberostemoninol (3) and bisdehydroneotuberostemonine (4), were isolated from Stemona
Binary chromatographic fingerprint analysis of Stemonae Radix from three Stemona plants and its applications
TLDR
The results indicate that the chemical constituents from different parts of the underground material of Stemona plants are diverse and that the processing methods affect certain constituents in the root tuber samples, and show that the binary chromatographic fingerprint method can be used to differentiate the three officialStemona species or the adulterants of SR.
Rapid structural determination of alkaloids in a crude extract of Stemona saxorum by high-performance liquid chromatography/electrospray ionization coupled with tandem mass spectrometry.
TLDR
A reversed-phase high-performance liquid chromatography with tandem mass spectrometry (RP-HPLC/MS(n) method was developed for the characterization of Stemona alkaloids with a pyrido[1,2-a]azepine A,B-ring core from the extract of S. saxorum.
Structural relationships of stemona alkaloids: assessment of species-specific accumulation trends for exploiting their biological activities.
On the basis of a comparison of 42 Stemona samples, representing eight different species collected and cultivated in Thailand, species-specific accumulation trends of Stemona alkaloids were analyzed.
Antitussive effects of Stemona tuberosa with different chemical profiles.
Alkaloids from the Roots of Stemona cochinchinensis
Phytochemical investigation of the roots of Stemona cochinchinensis led to the isolation and structure elucidation of a new pyrido[1,2-a]azepine-type alkaloid, stemocochinamine (1), and of four new
Simultaneous quantification of six alkaloid components from commercial stemonae radix by solid phase extraction-high-performance liquid chromatography coupled with evaporative light scattering detector
TLDR
This article provides an accurate and simple analytical method for quality survey of commercial stemonae radix and suggests careful selection of Stemona sources with obvious antitussive value but devoid of croomine followed by good agricultural practice and good manufacturing practice process is suggested.
General Fragmentations of Alkaloids in Electrospray Ionization Tandem Mass Spectrometry
Various types of alkaloids observed in several herbal medicines were analyzed by electrospray ionization tandem mass spectrometry in positive ion mode. In the present study, MS/MS spectralpatterns
...
1
2
3
4
...

References

SHOWING 1-10 OF 11 REFERENCES
Antitussive activity of Stemona alkaloids from Stemona tuberosa.
TLDR
It is demonstrated, for the first time, that compounds 1 and 5 showed significant antitussive activities in guinea pig after cough induction by citric acid aerosol stimulation.
The stemona alkaloids.
Structure of alkaloid 275A, a novel 1-azabicyclo[5.3.0]decane from a dendrobatid frog, Dendrobates lehmanni: synthesis of the tetrahydrodiastereomers.
The principal alkaloid 275A in skins of the Colombian poison frog Dendrobates lehmanni has been identified as the pyrrolo[1,2-a]azepane (1), the first occurrence in nature of this "izidine" system.
The Families of the Monocotyledons: Structure, Evolution, and Taxonomy
TLDR
The Monocotyledons are studied as a model for understanding the evolution of phytochemical characters in fruit and seed establishment and the role of ornamentation in theecycle of a fruit.
APPLICATIONS OF VINYLOGOUS MANNICH REACTIONS. CONCISE ENANTIOSPECIFIC TOTAL SYNTHESES OF (+)-CROOMINE
Because the vinylogous Mannich reaction of substituted furans with iminium ions is a useful construction in alkaloid synthesis, it is important to know what effects substituents on the two reacting
Asymmetric Synthesis of Polyfunctionalized Pyrrolidines and Related Alkaloids
This account describes our recent studies on the develop- ment of a general method of preparing polyfunctionalized pyrroli- dine, indolizidine, pyrrolizidine and pyrrolo(1,2-a)azepines and their
...
1
2
...