Analogs of the antimicrobial peptide trichogin having opposite membrane properties.

@article{Epand2001AnalogsOT,
  title={Analogs of the antimicrobial peptide trichogin having opposite membrane properties.},
  author={Richard M Epand and Fernando Formaggio and Marco Crisma and Huiyuan Wu and Robert I. Lehrer and C. Toniolo},
  journal={European journal of biochemistry},
  year={2001},
  volume={268 3},
  pages={703-12}
}
Four analogs of the antimicrobial peptide trichogin GA IV were studied. Their sequences are as follows: GT, n-octanoyl-Aib-Gly-Leu-Aib-Gly-Gly-Leu-Aib-Gly-Ile-Leu-OMe; ST, n-octanoyl-Aib-Ser-Leu-Aib-Ser-Ser-Leu-Aib-Ser-Ile-Leu-OMe; BT, n-octanoyl-Aib-Ser(tBu)-Leu-Aib-Ser(tBu)-Ser(tBu)-Leu-Aib-Ser(tBu)-Ile-Leu-OMe; and DT, n-octanoyl-Aib-Ser(tBu)-Leu-Aib-Ser… CONTINUE READING