Analgesic efficacy and safety of tramadol enantiomers in comparison with the racemate: a randomised, double-blind study with gynaecological patients using intravenous patient-controlled analgesia.

@article{Grond1995AnalgesicEA,
  title={Analgesic efficacy and safety of tramadol enantiomers in comparison with the racemate: a randomised, double-blind study with gynaecological patients using intravenous patient-controlled analgesia.},
  author={Stefan Grond and Thomas Meuser and D F Zech and Ulf Hennig and K. Lehmann},
  journal={Pain},
  year={1995},
  volume={62 3},
  pages={313-20}
}
The opioid analgesic tramadol is a racemate and consists of 50% (+)- and 50% (-)-enantiomer. This study investigated analgesic efficacy and safety of both enantiomers after intravenous (i.v.) injection in comparison with the racemate. Ninety-eight patients recovering from major gynaecological surgery under opioid-free halothane anaesthesia were treated in a… CONTINUE READING