Analgesic effects of serotonin and receptor-selective serotonin agonists in the rat spinal cord.

@article{Crisp1991AnalgesicEO,
  title={Analgesic effects of serotonin and receptor-selective serotonin agonists in the rat spinal cord.},
  author={Tracey Crisp and J L Stafinsky and L J Spanos and Martin Uram and Valentina Perni and H B Donepudi},
  journal={General pharmacology},
  year={1991},
  volume={22 2},
  pages={247-51}
}
1. Serotonin (5-HT) and selective 5-HT receptor agonists were administered intrathecally (i.t.) in rats, and the antinociceptive efficacy of these agents was assessed on the tail-flick and hot plate tests. 2. The 5-HT receptor agonists examined in this study included the 5-HT1A agonist 8-hydroxy-N,N-dipropyl-2-aminotetralin (8-OH-DPAT), the 5-HT1B agonist m-trifluoromethylphenylpiperazine (TFMPP), the 5-HT2 agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and the 5-HT3 agonist… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

Similar Papers

Loading similar papers…