Analgesic effects of mad honey (grayanotoxin) in mice models of acute pain and painful diabetic neuropathy.

@article{Gunduz2014AnalgesicEO,
  title={Analgesic effects of mad honey (grayanotoxin) in mice models of acute pain and painful diabetic neuropathy.},
  author={A. Erkam Gunduz and Ismet Eraydin and Suha Turkmen and Omer Faruk Kalkan and Suleyman Turedi and Umut Eryiğit and Ahmet Ayar},
  journal={Human & experimental toxicology},
  year={2014},
  volume={33 2},
  pages={130-5}
}
OBJECTIVES The aim of this experimental study was to investigate the effects of mad honey (grayanotoxin, GTX), used in complementary medicine for a variety of purposes besides being food, on pain thresholds in normal mice as model for acute pain and diabetic mouse as model for neuropathic pain. METHODS Hind paw withdrawal pain threshold to thermal stimulus was measured with a plantar analgesia meter in a mice model using healthy intact animals for acute pain and streptozotocin-induced… CONTINUE READING