Analgesic effect of the synthetic cannabinoid CT-3 on chronic neuropathic pain: a randomized controlled trial.

@article{Karst2003AnalgesicEO,
  title={Analgesic effect of the synthetic cannabinoid CT-3 on chronic neuropathic pain: a randomized controlled trial.},
  author={Matthias Karst and Kahlid Salim and Sumner H. Burstein and Ingomar Conrad and Ludwig Hoy and Udo Schneider},
  journal={JAMA},
  year={2003},
  volume={290 13},
  pages={
          1757-62
        }
}
CONTEXT 1',1'dimethylheptyl-Delta8-tetrahydrocannabinol-11-oic acid (CT-3), a potent analog of THC-11-oic acid, produces marked antiallodynic and analgesic effects in animals without evoking the typical effects described in models of cannabinoids. Therefore, CT-3 may be an effective analgesic for poorly controlled resistant neuropathic pain. OBJECTIVE To examine the analgesic efficacy and safety of CT-3 in chronic neuropathic pain in humans. DESIGN AND SETTING Randomized, placebo-controlled… CONTINUE READING
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