Analgesic effect of histamine induced by intracerebral injection into mice

Abstract

Three methods were used to study the analgesic effect of intracerebral injection of histamine (Hi) on mice: the writhing test (acetic acid and phenylquinone), the electrical stimulation of the tail and the hot plate test. At doses higher than 2 μg, Hi inhibited the writhing syndrome significantly, and at doses of 10 μg or higher, Hi displayed a marked… (More)
DOI: 10.1007/BF01972339

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@article{Chung1984AnalgesicEO, title={Analgesic effect of histamine induced by intracerebral injection into mice}, author={Yoon Hoo Chung and Hiroaki Miyake and Chiaki Kamei and Kenji Tasaka}, journal={Agents and Actions}, year={1984}, volume={15}, pages={137-142} }