Analgesic effect and plasma concentrations of codeine and morphine after two dose levels of codeine following oral surgery

@article{Quiding2004AnalgesicEA,
  title={Analgesic effect and plasma concentrations of codeine and morphine after two dose levels of codeine following oral surgery},
  author={Hans Quiding and G Lundqvist and Lars O. Bor{\'e}us and U. G. Bondesson and John {\"O}hrvik},
  journal={European Journal of Clinical Pharmacology},
  year={2004},
  volume={44},
  pages={319-323}
}
SummaryA double blind randomised cross over investigation was carried out in 25 male patients undergoing two oral surgical extractions, one for each lower wisdom tooth. The two extractions were performed about 6 weeks apart and were carried out under local anaesthesia. One hour after each extraction the patients randomly received 90 or 45 mg codeine. During the following 5 h the patients rated the intensity of their pain on a visual analogue scale. Blood was simultaneously sampled and assayed… 
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