Analgesic and antiinflammatory effects of 2-(10,11-dihydro-10-oxo-dibenzo[b,f]thiepin-2-yl)propionic acid in rat and mouse.

@article{Kameyama1987AnalgesicAA,
  title={Analgesic and antiinflammatory effects of 2-(10,11-dihydro-10-oxo-dibenzo[b,f]thiepin-2-yl)propionic acid in rat and mouse.},
  author={Tsutomu Kameyama and Toshitaka Nabeshima and Shigeyuki Yamada and Masayuki Sato},
  journal={Arzneimittel-Forschung},
  year={1987},
  volume={37 1},
  pages={19-26}
}
Analgesic and antiinflammatory effects of 2-(10,11-dihydro-10-oxo-dibenzo[b,f]thiepin-2-yl)propionic acid (CN-100) have been investigated pharmacologically in rats and mice. With bradykinin-induced pain responses, CN-100 proved to be the most potent of the commercial non-steroidal antiinflammatory drugs which were tested in rats: The potency of CN-100 was 4… CONTINUE READING