• Corpus ID: 97932266

Analgesic and Anti-Inflammatory Activities of Dichrostachys glomerata (Forssk.) Hutch. Fruits Methanolic Extract in Rats

@article{Gisle2012AnalgesicAA,
  title={Analgesic and Anti-Inflammatory Activities of Dichrostachys glomerata (Forssk.) Hutch. Fruits Methanolic Extract in Rats},
  author={Gis{\`e}le A Kiki Gis{\`e}le and Desire Paul Djomeni Dzeufiet and Harquin Simplice Foyet and Paulin Nana and C{\'e}lestin Dogmo Sokeng and Th{\'e}ophile Dimo and Pi{\`e}rre Kamtchouing},
  journal={Journal of Physiology and Pharmacology Advances},
  year={2012},
  volume={2},
  pages={269-276}
}
The present study has been undertaken to assess the analgesic and the anti-inflammatory properties of methanolic extract Dichrostachys glomerata fruit. Pain was induced in mice by the intraperitoneal administration of 1 % acetic acid, and formalin. Carrageenan and histamin (1%) were used to induce inflammation in rat paws. At the doses of 25 and 50 mg/kg, D. glomerata significantly inhibited pain induced by acetic acid with a percentage inhibition of 80.0 and 76.0 %, respectively. The… 
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References

SHOWING 1-10 OF 27 REFERENCES
Anti-inflammatory and analgesic activities of the aqueous extracts of Margaritaria discoidea (Euphorbiaceae) stem bark in experimental animal models.
TLDR
Acute toxicity test showed that the plant may be safe for pharmacological uses and provided some justification for the folkloric use of the plant in several communities for conditions such as stomachache, pain and inflammations.
Effects of Hibiscus asper leaves extracts on carrageenan induced oedema and complete Freund's adjuvant-induced arthritis in rats
TLDR
Observations suggest possible therapeutic potential of the methanolic extract of H. asper leaves in inflammatory disorders like rheumatoid arthritis in Wistar albino rats.
Analgesic, antipyretic and anti-inflammatory properties of Euphorbia hirta.
TLDR
It is concluded that this plant extract exerts central analgesic properties and remained inactive on chronic processes such as Freund's adjuvant-induced rheumatoid arthritis, if inefficacy was observed on rat backpaws edema and on loss of weight, the aqueous extract reduced the inflammatory hyperalgia.
The Analgesic Effect of Tribulus terrestris Extract and Comparison of Gastric Ulcerogenicity of the Extract with Indomethacine in Animal Experiments
TLDR
The results of ulcerogenic studies indicate that the gastric ulcerogenecity of plant extract is lower than the indomethacin in the rat's stomach, and it can be concluded that T. terrestris extract has a suitable analgesic effect.
Antinociceptive and anti-inflammatory effects of Crocus sativus L. stigma and petal extracts in mice
TLDR
It is concluded that aqueous and ethanolic extracts of saffron stigma and petal have an antinociceptive effect, as well as acute and/or chronic anti-inflammatory activity.
Analgesic Effects of Callus Culture Extracts from Selected Species of Phyllanthus in Mice
TLDR
The results indicate that, similar to previous reported data from the extract of P. corcovadensis, the methanolic extracts of callus culture of Phyllanthus tenellus exhibit potent analgesic properties against neurogenic and inflammatory pain that seem to be unrelated to the activation of opioid mechanisms.
Antinociceptive and antipyretic activities of Pongamia pinnata leaves
TLDR
It is demonstrated that PLE possesses marked antinociceptive as well as antipyretic activities and thus scientifically validated its use in the treatment of pain and pyretic disorders.
Effects of chlomipramine and fluoxetine on subcutaneous carrageenin-induced inflammation in the rat
TLDR
The results confirm that antidepressant drugs are able to reduce the development of inflammation in the rat and suggest that the inhibition of substance P production might play a role in mediating the anti-inflammatory effects of chlomipramine.
Research Paper - ANTI-INFLAMMATORY AND ANTIOXIDANT ACTIVITIES OF CASSIA FISTULA LINN BARK EXTRACTS
TLDR
It could be concluded that Cassia fistula bark extracts (CFA & CFM) possess significant anti-inflammatory and anti oxidant properties.
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