Analgesic activity of ethanolic extract of Manihot esculenta Crantz leaves in mice

  title={Analgesic activity of ethanolic extract of Manihot esculenta Crantz leaves in mice},
  author={Isnatin Miladiyah and Ferdiyanto Dayi and Sufi Desrini},
Cassava (Manihot esculenta Crantz) leaves have long been used as a vegetable in many countries and empirically as a febrifuge. The aim of the present study was to evaluate the analgesic activity of an ethanolic extract of cassava leaves in mice. Thirty Balb/c mice (20-30 g, 2-3 months old) were randomly divided into 6 groups. Group I was given distilled water 1 mL as negative control, group II paracetamol 65 mg/kgBW as positive control, and group III-VI received an ethanolic extract of cassava… CONTINUE READING


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