Analgesic activity of 3-mono-substituted derivatives of dihydrofuran-2-one in experimental rodent models of pain.

@article{Saat2009AnalgesicAO,
  title={Analgesic activity of 3-mono-substituted derivatives of dihydrofuran-2-one in experimental rodent models of pain.},
  author={Kinga Sałat and Barbara Filipek and Krzysztof Więckowski and Barbara Malawska},
  journal={Pharmacological reports : PR},
  year={2009},
  volume={61 5},
  pages={807-18}
}
Three derivatives of dihydrofuran-2-one (L-PP, L-PP1, and L-SAL) were administered by intraperitoneal injection and their analgesic activity was assayed in several models of pain. The activity of these derivatives were tested using a hot plate test, a writhing test, capsaicin- and glutamate-induced nociception, along with two models of local anesthesia… CONTINUE READING