Analgesic Efficacy of Controlled‐Release Oxycodone in Postoperative Pain

  title={Analgesic Efficacy of Controlled‐Release Oxycodone in Postoperative Pain},
  author={A. Sunshine and N. Olson and A. Colon and J. Rivera and R. Kaiko and R. Fitzmartin and R. Reder and P. Goldenheim},
  journal={The Journal of Clinical Pharmacology},
  • A. Sunshine, N. Olson, +5 authors P. Goldenheim
  • Published 1996
  • Medicine
  • The Journal of Clinical Pharmacology
  • The efficacy and safety of graded doses (10, 20, and 30 mg) of controlled‐release (CR) oxycodone was compared with that of immediate‐release (IR) oxycodone (15 mg), immediate‐release oxycodone 10 mg in combination with acetaminophen 650 mg (APAP), and placebo in a single‐dose, double‐blind, randomized, parallel‐group study. The participants, 182 inpatients experiencing moderate to severe pain after abdominal or gynecologic surgery, provided hourly ratings of pain intensity and relief for 12… CONTINUE READING
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    Paper Mentions

    The main hypothesis of this study is that preoperative administration of controlled-release (CR) oxycodone may reduce acute postoperative pain and improve time to discharge from the… Expand
    ConditionsAnesthesia Recovery Period, Pain, Postoperative
    InterventionDrug, Procedure
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