Analgesic Efficacy of Controlled‐Release Oxycodone in Postoperative Pain

@article{Sunshine1996AnalgesicEO,
  title={Analgesic Efficacy of Controlled‐Release Oxycodone in Postoperative Pain},
  author={Abraham Sunshine and Nancy Z. Olson and A. Colon and Juana Rivera and Robert Francis Kaiko and Ronald D. Fitzmartin and Robert F. Reder and Paul D. Goldenheim},
  journal={The Journal of Clinical Pharmacology},
  year={1996},
  volume={36}
}
The efficacy and safety of graded doses (10, 20, and 30 mg) of controlled‐release (CR) oxycodone was compared with that of immediate‐release (IR) oxycodone (15 mg), immediate‐release oxycodone 10 mg in combination with acetaminophen 650 mg (APAP), and placebo in a single‐dose, double‐blind, randomized, parallel‐group study. The participants, 182 inpatients experiencing moderate to severe pain after abdominal or gynecologic surgery, provided hourly ratings of pain intensity and relief for 12… 
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TLDR
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TLDR
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