Corpus ID: 18288847

Analgesia Fucoidan protects against dopaminergic neuron death in vivo and in vitro

  title={Analgesia Fucoidan protects against dopaminergic neuron death in vivo and in vitro},
  author={Ding-zhen Luo and Quanbin Zhang and Haomin Wang and Yan-qiu Cui and Zuoli Sun and Jian Yang and Yan Zheng and Jun Jia and Fen Yu and Xuan Wang and Xiaomin Wang},
a r t i c l e i n f o Keywords: Fucoidan Neuroprotection Antioxidant activity Oxidative stress 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine Parkinson's disease Parkinson's disease is a neurodegenerative disorder of uncertain pathogenesis characterized by a loss of dopaminergic neurons in substantia nigra pars compacta, and can be modeled by the neurotoxin 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP). Oxidative stress may contribute to MPTP-and Parkinson's disease-related… Expand

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  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 2001
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