Anal sphincter dysfunction in Parkinson's disease.

@article{Mathers1989AnalSD,
  title={Anal sphincter dysfunction in Parkinson's disease.},
  author={S E Mathers and P. A. Kempster and Penelope J. Law and J. P. Frankel and Clive I. Bartram and Andrew John Lees and Gerald M. Stern and Michael Swash},
  journal={Archives of neurology},
  year={1989},
  volume={46 10},
  pages={
          1061-4
        }
}
Striated anal sphincter function was studied electrophysiologically and radiologically in six patients with Parkinson's disease and chronic constipation. In five cases, there was paradoxic anal sphincter muscle contraction during simulated defecation straining resembling anismus-type pelvic outlet obstruction. Radiologic studies showed functional improvement of the defecatory mechanism following the administration of the dopamine receptor agonist apomorphine in four patients. Dysfunction of the… Expand
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