Anal human papillomavirus infection and associated neoplastic lesions in men who have sex with men: a systematic review and meta-analysis.

@article{Machalek2012AnalHP,
  title={Anal human papillomavirus infection and associated neoplastic lesions in men who have sex with men: a systematic review and meta-analysis.},
  author={Dorothy A Machalek and Mary Poynten and Fengyi Jin and Christopher K Fairley and Annabelle Farnsworth and Suzanne Marie Garland and Richard John Hillman and Kathy Petoumenos and Jennifer Margaret Roberts and Sepehr N Tabrizi and David James Templeton and Andrew Edwin Grulich},
  journal={The Lancet. Oncology},
  year={2012},
  volume={13 5},
  pages={487-500}
}
BACKGROUND Men who have sex with men (MSM) are at greatly increased risk of human papillomavirus (HPV)-associated anal cancer. Screening for the presumed cancer precursor, high-grade anal intraepithelial neoplasia (AIN), followed by treatment in a manner analogous to cervical screening, has been proposed. We aimed to assess available data for anal HPV disease that can inform pre-cancer screening programmes. METHODS We searched PubMed, OVID Medline, and Embase for all studies published before… CONTINUE READING
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