Anaesthetic Potency of CF4 and SF6 in Dogs

@article{Miller1969AnaestheticPO,
  title={Anaesthetic Potency of CF4 and SF6 in Dogs},
  author={STANLEY L. Miller and EDMOND I. Eger and C. Lundgren},
  journal={Nature},
  year={1969},
  volume={221},
  pages={468-469}
}
  • STANLEY L. Miller, EDMOND I. Eger, C. Lundgren
  • Published 1969
  • Chemistry, Medicine
  • Nature
  • THERE are two types of physicochemical theory of general anaesthesia. The Meyer–Overton and related theories correlate the potency of an anaesthetic with its solubility in lipids1–3, implying that the site of action of the anaesthetic gas is in the lipid part of the nerve membrane. The hydrate theories4,5 correlate the potency of an anaesthetic with its hydrate dissociation pressure, implying that the site of action of the anaesthetic is in the aqueous phase in or near the nerve membrane. For… CONTINUE READING
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