Anaerobic regulation of Bacillus subtilis Krebs cycle genes.

  title={Anaerobic regulation of Bacillus subtilis Krebs cycle genes.},
  author={Michiko M. Nakano and Peter Zuber and Abraham L. Sonenshein},
  journal={Journal of bacteriology},
  volume={180 13},
Krebs cycle enzyme activity in Bacillus subtilis was examined under aerobic and anaerobic conditions. Citrate synthase and aconitase activities in cells grown anaerobically in the presence of nitrate were reduced by as much as 10- and 30-fold, respectively, from levels observed under aerobic culture conditions. The maximum level of isocitrate dehydrogenase activity during anaerobic growth was only twofold lower than that in aerobic cultures. These reductions in activity under conditions of… CONTINUE READING