Anaerobic osteomyelitis. A new experimental rabbit model.

  title={Anaerobic osteomyelitis. A new experimental rabbit model.},
  author={Annika Johansson and Olle Svensson and Gudmund Blomgren and Glen Eliasson and Carl Erik Nord},
  journal={Clinical orthopaedics and related research},
Experimental studies of osteomyelitis have been hampered by methodologic problems. For inducing experimental anaerobic osteomyelitis, the medullary cavity of the proximal tibial metaphysis of five New Zealand white rabbits was excavated and filled with a polyvinyl alcohol sponge. On the right side, 1 ml of a suspension containing Bacteroides fragilis (10(7) colony-forming units/ml) was injected, while on the left side, Ringer's solution was used as a control substance. Within five weeks, all… CONTINUE READING