Anaerobic antimicrobial therapy after necrotizing enterocolitis in VLBW infants.

  title={Anaerobic antimicrobial therapy after necrotizing enterocolitis in VLBW infants.},
  author={Julie Autmizguine and Christoph P. Hornik and Matthew Laughon and Reese H. Clark and Charles Michael Cotten and Michael Cohen-Wolkowiez and Daniel Kelly Benjamin and Phillip Brian Smith},
  volume={135 1},
OBJECTIVE To evaluate the effect of anaerobic antimicrobial therapy for necrotizing enterocolitis (NEC) on clinical outcomes in very low birth weight (≤1500 g) infants. METHODS We identified very low birth weight infants with NEC from 348 US NICUs from 1997 to 2012. Anaerobic antimicrobial therapy was defined by antibiotic exposure on the first day of NEC. We matched (1:1) infants exposed to anaerobic antimicrobial therapy with infants who were not exposed by using a propensity score… CONTINUE READING
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