Anaerobic acetate oxidation to CO2 by Desulfotomaculum acetoxidans

@article{Spormann2004AnaerobicAO,
  title={Anaerobic acetate oxidation to CO2 by Desulfotomaculum acetoxidans},
  author={Alfred M. Spormann and Rudolf K Thauer},
  journal={Archives of Microbiology},
  year={2004},
  volume={150},
  pages={374-380}
}
Desulfotomaculum acetoxidans has been proposed to oxidize acetate to CO2 via an oxidative acetyl-CoA/carbon monoxide dehydrogenase pathway rather than via the citric acid cycle. We report here the presence of the enzyme activities required for the operation of the novel pathway. In cell extracts the following activities were found (values in brackets=specific activities and apparent Km; 1 U·mg-1=1 μmol·min-1·mg protein-1 at 37°C): Acetate kinase (6.3 U·mg-1; 2 mM acetate; 2.4 mM ATP); phosphate… Expand

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