Anaemia of acute malaria infections in non-immune patients primarily results from destruction of uninfected erythrocytes.

@article{Jakeman1999AnaemiaOA,
  title={Anaemia of acute malaria infections in non-immune patients primarily results from destruction of uninfected erythrocytes.},
  author={G. Jakeman and A. Saul and W. Hogarth and W. Collins},
  journal={Parasitology},
  year={1999},
  volume={119 ( Pt 2)},
  pages={
          127-33
        }
}
While anaemia has long been recognized as a consequence of acute infections with malaria, the relative contributions of direct erythrocyte destruction by parasites, destruction of uninfected erythrocytes and changes in erythropoiesis have been unclear. Fitting of parasitaemia and anaemia data from neurosyphilis patients undergoing malaria therapy to a mathematical model shows that in these patients, an average of 8.5 erythrocytes were destroyed in addition to each erythrocyte observed to become… Expand
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