Anacardic acid attenuates pressure‐overload cardiac hypertrophy through inhibiting histone acetylases

@inproceedings{Li2019AnacardicAA,
  title={Anacardic acid attenuates pressure‐overload cardiac hypertrophy through inhibiting histone acetylases},
  author={Shuo Li and Bohui Peng and Xiaomei Luo and Huichao Sun and Chang Peng},
  booktitle={Journal of cellular and molecular medicine},
  year={2019}
}
Cardiac hypertrophy has become a major cardiovascular problem wordwide and is considered the early stage of heart failure. Treatment and prevention strategies are needed due to the suboptimal efficacy of current treatment methods. Recently, many studies have demonstrated the important role of histone acetylation in myocardium remodelling along with cardiac hypertrophy. A Chinese herbal extract containing anacardic acid (AA) is known to possess strong histone acetylation inhibitory effects. In… CONTINUE READING

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