Anabolic steroids in sport: biochemical, clinical and analytical perspectives

  title={Anabolic steroids in sport: biochemical, clinical and analytical perspectives},
  author={Andrew T. Kicman and D. B. Gower},
  journal={Annals of Clinical Biochemistry},
  pages={321 - 356}
International Olympic Committee accredited laboratories play a key role in upholding the principle of fair play and innate ability, as desired by the majority of sports competitors and spectators. Not only does doping damage the image of sport, but it can also be harmful to the individual. The great majority of samples test negative but, when an adverse finding is declared, the analytical data must be of a sufficiently high standard to withstand legal challenges by third parties. The most… 

Pharmacology of anabolic steroids

  • A. Kicman
  • Biology, Medicine
    British journal of pharmacology
  • 2008
Anabolic steroids are being considered for the treatment of cachexia associated with chronic disease states, and to address loss of muscle mass in the elderly, but nevertheless their efficacy still needs to be demonstrated in terms of improved physical function and quality of life.

Metabolism of anabolic steroids and their relevance to drug detection in horseracing.

The aim of this paper is to review current knowledge of the metabolism of appropriate steroids, the current approaches to their detection in equine sport and future trends that may affect equine dope testing.

Anabolic steroid use: patterns of use and detection of doping.

Anabolic-androgenic steroids (AAS) were the first identified doping agents that have ergogenic effects and are being used to increase muscle mass and strength in adult males. Consequently, athletes

Knowledge and Attitudes of Amateur Sports Participants Regarding the Cardiac Risks Associated With the Use of Anabolic-Androgenic Steroids

The knowledge of the cardiac risks associated with the use of anabolic steroids amongst amateur sports participants was generally poor and efforts must be made to educate coaches and gym facilities about the harmful effects of certain performance enhancing drugs.

Androgens, sports, and detection strategies for anabolic drug use.

Contemporary Patterns of Anabolic Steroids Abuse and Associated Short Term Side Effects in Athletes

Conclusions: Contemporary AS users consistently practice overdose polypharmacy and knowledge of this type of abuse can be beneficial for the treatment of the side effects.

Metabolism and excretion of anabolic steroids in doping control—New steroids and new insights

  • P. EenooF. Delbeke
  • Biology, Medicine
    The Journal of Steroid Biochemistry and Molecular Biology
  • 2006

Public health impact and implications of the use of anabolic androgenic steroids (AAS) and associated drugs amongst the male general population

This research has made a significant contribution to the recognition and understanding of the harms associated with the administration of these drugs through injection and the impact of adulterated products as a result of the illicit market.

Anabolic Steroids: Metabolism, Doping and Detection in Human and Equestrian Sports

This chapter highlights the important aspects of detection of doping with synthetic anabolic steroids and discusses some of the problems with, and solutions to, the detection of misuse of the

Doping in sports : the effect of alcohol on the urinary increase of testosterone I epitestosterone

Serum analysis showed a decrease in T in males, which indicates that the increase in urinary T/E is most likely due to an increase in the hepatic formation of T glucuronide, which is rapidly excreted, not to a increase in gonadal production.



Anabolic steroids: Metabolism, doping and detection in equestrian and human sports

During the 1960s, many pharmaceutically licensed chemical analogues of testosterone were released on to the market, these analogues being designed to enhance the anabolic effect for clinical purposes but competitors also desired these drugs, wanting the muscle building effects of testosterone but without the androgenic effects.

Anabolic steroids: the gremlins of sport.

  • T. Todd
  • Education
    Journal of sport history
  • 1987
An attempt to provide a chronology and an insight into this baleful aspect of modern sport of athletes using anabolic steroids.

Doping in sport: misuse, analytical tests, and legal aspects.

The proceedings of this symposium, published in this issue of Clinical Chemistry, bring together health, social, endocrine, and analytical perspectives in a widely read peer-reviewed journal.

Anabolic steroids: A review of the literature

A detailed review of the literature on anabolic steroids is provided that provides the reader the information needed to make an informed decision on the relative risks and benefits of anabolic steroid to the athlete.

Anabolic steroid abuse

Education alone is probably not the answer to stopping anabolic steroid abuse but is an essential first step in combating this problem, physicians should avoid condemning individuals who choose to use anabolic steroids and encourage discussion of use with their health providers.

Hormonal doping and androgenization of athletes: a secret program of the German Democratic Republic government.

Several classified documents saved after the collapse of the German Democratic Republic (GDR) in 1990 describe the promotion by the government of the use of drugs, notably androgenic steroids, in

Issues in detecting abuse of xenobiotic anabolic steroids and testosterone by analysis of athletes' urine.

Among ancillary tests to help discriminate between naturally increased T/E values and those reflecting T use, the most promising is determination of the carbon isotope ratio.

Recent Developments in the Toxicology of Anabolic Steroids

The anabolic steroids are toxic drugs with both long and short term effects, and their abuse by athletes is to be decried, particularly in view of the frequent and prolonged use by the young.

Detection of anabolic steroid administration to athletes.