Anabolic effect of daidzein on cortical bone in tissue culture: Comparison with genistein effect

@article{Gao2004AnabolicEO,
  title={Anabolic effect of daidzein on cortical bone in tissue culture: Comparison with genistein effect},
  author={Y. Gao and M. Yamaguchi},
  journal={Molecular and Cellular Biochemistry},
  year={2004},
  volume={194},
  pages={93-98}
}
The effect of daidzein on cortical bone in vitro was investigated. Femoral-diaphyseal tissues obtained from elderly female rats were cultured for 24 h in Dulbecco's modified Eagle's medium (high glucose, 4.5%) supplementation with antibiotics and bovine serum albumin. The experimental cultures contained 10-7 to 10-5 M daidzein. The presence of daidzein (10-6 and 10-5 M) caused a significant increase of alkaline phosphatase activity, deoxyribonucleic acid (DNA) and calcium contents in bone… Expand
Stimulatory effect of genistein and daidzein on protein synthesis in osteoblastic MC3T3-E1 cells: Activation of aminoacyl-tRNA synthetase
Enhancing effect of daidzein on the differentiation and mineralization in mouse osteoblast-like MC3T3-E1 cells.
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