Anabolic agents and bone quality.

  title={Anabolic agents and bone quality.},
  author={Tarek A. Sibai and Elise Feng-I Morgan and Thomas A. Einhorn},
  journal={Clinical orthopaedics and related research},
  volume={469 8},
BACKGROUND The definition of bone quality is evolving particularly from the perspective of anabolic agents that can enhance not only bone mineral density but also bone microarchitecture, composition, morphology, amount of microdamage, and remodeling dynamics. QUESTIONS/PURPOSES This review summarizes the molecular pathways and physiologic effects of current and potential anabolic drugs. METHODS From a MEDLINE search (1996-2010), articles were identified by the search terms "bone quality… CONTINUE READING

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