An update on the use of helminths to treat Crohn’s and other autoimmunune diseases

@article{Reddy2008AnUO,
  title={An update on the use of helminths to treat Crohn’s and other autoimmunune diseases},
  author={Aditya Reddy and Bernard Fried},
  journal={Parasitology Research},
  year={2008},
  volume={104},
  pages={217-221}
}
This review updates our previous one (Reddy and Fried, Parasitol Research 100: 921–927, 2007) on Crohn’s disease and helminths. The review considers the most recent literature on Trichuris suis therapy and Crohn’s and the significant literature on the use of Necator americanus larvae to treat Crohn’s and other autoimmune disorders. The pros and cons of helminth therapy as related to autoimmune disorders are discussed in the review. We also discuss the relationship of the bacterium Campylobacter… 
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TLDR
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TLDR
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TLDR
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TLDR
An overview of the infections postulated as being relevant to the onset of IBD is given, in addition to reviewing current knowledge regarding other microorganisms that are associated with modifying the risk of developing IBD.
Helminth/Parasite Treatment of Multiple Sclerosis
  • J. Correale
  • Biology, Medicine
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  • 2014
TLDR
It is strongly recommended that live helminth or ova parasites be administered only to individuals participating in strictly monitored, controlled clinical trials, and much remains to be explored before the field can move from experimental animal models to application in clinical practice.
Biological role of excretory-secretory proteins in endemic parasites of Latin America and the Caribbean.
TLDR
Key information on the function of excretory/secretory proteins from these parasites in their infectivity, pathogeny and diagnosis is discussed and may lead to new approaches for the clinical management and diagnosis of these diseases.
Prerequisites for the pharmaceutical industry to develop and commercialise helminths and helminth-derived product therapy.
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