An update on pityriasis rosea and other similar childhood exanthems

  title={An update on pityriasis rosea and other similar childhood exanthems},
  author={John C. Browning},
  journal={Current Opinion in Pediatrics},
  • J. Browning
  • Published 1 August 2009
  • Medicine
  • Current Opinion in Pediatrics
Purpose of review Pityriasis rosea is a common skin condition seen in children and adults. Whereas pityriasis rosea is a benign condition, it is important to distinguish it from other childhood exanthems. Recent findings Pityriasis rosea can present in a variety of manners. Most often a herald patch precedes the generalized eruption, although this is not always the case. Pityriasis rosea may lead to undesirable outcomes when affecting pregnant women. Guttate psoriasis, secondary syphilis… 

Unique clinical presentations of pityriasis rosea: aphthous ulcers, vesicles and inverse distribution of lesions.

Three cases of PR are illustrated including those that presented with aphthousulcers, vesicles, and an inverse pattern.

Diagnosis and management of pityriasis rosea.

Three factors that led to the infectious theory of pityriasis rosea include: • The course of the rash is typical in nature and is similar to other viral rash courses, such as varicella and measles, which lends to the theory that pityriases rosea is infectious in nature.

Atypical pityriasis rosea: clinical evaluation of 27 patients

Patients with atypical pityriasis rosea diagnosed by clinical and/or histopathological examination and applied to the outpatient clinic of dermatology department between the years 2007 and 2015 were analyzed retrospectively.

Unique clinical presentations of rosea: aphthous ulcers, vesicles and inverse distribution of lesions

Three cases of PR are illustrated including those that presented with aphthous ulcers, vesicles, and an inverse pattern to illustrate the lack of its characteristic manifestations.

An Atypical Case of Pityriasis Rosea Gigantea after Influenza Vaccination

A rare case of a suberythrodermic pityriasis rosea with gigantic plaques after an influenza vaccination is reported, and the possible triggers of atypical manifestations of such a common dermatological disease in the setting of an altered immunity are discussed.

L‐lysine therapy to control the clinical evolution of pityriasis rosea: Clinical case report and literature review

It is concluded that the administration of L‐lysine, in therapeutic doses, can be a safe alternative for the PR control, and shown positive results in reducing the number of annual manifestations and the healing time of the lesions.


The first case of atypical PR with hypopigmented lesions and a target-shape herald patch is presented, and it is shown that this variant is an acute, self-limiting papulosquamous exanthem.


The study concludes that Pityriasis Rosea is a self-limiting disease, more common in adolescent to adults with male preponderance, common in cooler part of the year, hence Erythromycin has reduced the total duration of the disease and signs and symptoms significantly, hence it is effective in Pities Rosea.

Current trends in pityriasis rosea

Various clinical aspects of the disease, including its typical and atypical forms, differential diagnoses and the current recommendation of treatment strategies are discussed.

Pityriasis rosea: a natural history of pediatric cases in theCentral Anatolia Region of Turkey.

The course of PR is similar in Turkish children and adults, and the high prevalence of pruritus in children with PR in Turkey was also significant.



Pityriasis rosea in infancy.

A typical case of pityriasis rosea is reported in a 16-month-old infant, and other cases in infancy are reviewed, including those in infancy of infants under 2 years of age.

Pityriasis rosea: An important papulosquamous disorder

Pityriasis rosea is a mild, self‐limited skin disease of unknown etiology that affects children and young adults and is characterized by an initial herald patch, followed by the development of salmon‐pink scaly macules which, when localized to the trunk, form along Langer's lines of cleavage.


The clinical and histopathologic findings made possible the diagnosis of an atypical variety of PR, a previously healthy 2-year-old boy seen for a cutaneous eruption of four days' evolution that could not be diagnosed on clinical grounds alone, but that had two rather characteristic histologic findings.

One-year review of pityriasis rosea at the National Skin Centre, Singapore.

  • Y. TayC. Goh
  • Medicine
    Annals of the Academy of Medicine, Singapore
  • 1999
The profile of pityriasis rosea seen at a referral skin centre in Singapore is similar to that reported in other countries except for a male predominance and absence of monthly variation.

One-year review of pityriasis rosea at the National Skin Centre, Singapore.

The pattern of pityriasis rosea in Singapore is similar to that reported in other countries except for a male predominance and absence of monthly variation.

Atypical presentations of pityriasis rosea: case presentations

  • A. ChuhV. ZawarA. Lee
  • Medicine
    Journal of the European Academy of Dermatology and Venereology : JEADV
  • 2005
It is believed that it is difficult to make a clear division to define typical and atypical PR, and it is important not to ascribe any unusual or atypicals skin eruption with PR unless other dermatoses have been excluded.

Azithromycin Does Not Cure Pityriasis Rosea

Azithromycin does not cure Pityriasis rosea, and a drug with fewer adverse effects and greater biological half-life is set out to study this common skin disorder in children.

Vesicular pityriasis rosea: an atypical presentation.

A rare atypical type of PR with vesicles on the erythematous macules and plaques is reported, seen most frequently in adolescents and young adults.

Pityriasis rosea.

  • E. G. Little
  • Medicine
    Proceedings of the Royal Society of Medicine
  • 1908
The symptoms of pityriasis rosea can last anywhere from several weeks to several months. The first symptom usually is a characteristic skin rash, or lesion, on the chest or back region known as a

Pityriasis Rosea Unilateralis

A 34-year-old black woman presented at Cook County Dermatology Clinic with a two-month history of slightly pruritic, oval, hyperpigmented maculp'i, involving only the lett side of her Irunk, which regressed and disappeared seven weeks after the date of onset.