An update on nuclear calcium signalling.

@article{Bootman2009AnUO,
  title={An update on nuclear calcium signalling.},
  author={Martin D Bootman and Claire J Fearnley and Ioannis Smyrnias and Fraser MacDonald and H Llewelyn Roderick},
  journal={Journal of cell science},
  year={2009},
  volume={122 Pt 14},
  pages={2337-50}
}
Over the past 15 years or so, numerous studies have sought to characterise how nuclear calcium (Ca2+) signals are generated and reversed, and to understand how events that occur in the nucleoplasm influence cellular Ca2+ activity, and vice versa. In this Commentary, we describe mechanisms of nuclear Ca2+ signalling and discuss what is known about the origin and physiological significance of nuclear Ca2+ transients. In particular, we focus on the idea that the nucleus has an autonomous Ca2… CONTINUE READING
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