An update on niche composition, signaling and functional regulation of the adipose-derived stem cells.

@article{Kim2014AnUO,
  title={An update on niche composition, signaling and functional regulation of the adipose-derived stem cells.},
  author={Won-Serk Kim and Juhee Han and Sung-Joo Hwang and Jong-Hyuk Sung},
  journal={Expert opinion on biological therapy},
  year={2014},
  volume={14 8},
  pages={1091-102}
}
INTRODUCTION The self-renewal and differentiation of stem cells are controlled by both intrinsic factors and the surrounding microenvironment, which is known as the stem cell niche. Although the niches of adipose-derived stem cells (ASCs) are composed of diverse factors within the adipose tissue, the mechanisms by which niches are maintained, regulated and harmonized to support the ASCs are just beginning to be discovered. AREAS COVERED This review introduces the recent advances in the… CONTINUE READING
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