An update on molecular biology of thyroid cancers.

  title={An update on molecular biology of thyroid cancers.},
  author={Ozgur Omur and Yusuf Baran},
  journal={Critical reviews in oncology/hematology},
  volume={90 3},
Differentiated thyroid cancer (DTC) is the most common endocrinological malignancy. There are several histological variants such as papillary and follicular thyroid carcinoma. Many patients with well-differentiated subtypes of DTC are cured by surgery alone or with radioiodine, while poorly differentiated types usually have a worse prognosis. The aggressiveness of thyroid tumors is closely linked to specific gene alterations. Several diagnostic and prognostic molecular markers such as BRAF and… CONTINUE READING
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