An update of prophylactic human papillomavirus L1 virus-like particle vaccine clinical trial results.

  title={An update of prophylactic human papillomavirus L1 virus-like particle vaccine clinical trial results.},
  author={John T. Schiller and Xavier Castellsagu{\'e} and Luisa L. Villa and Allan Hildesheim},
  volume={26 Suppl 10},
This review focuses on recent publications of clinical trials of two prophylactic human papillomavirus (HPV) vaccines: Gardasil (Merck & Co., Inc., Whitehouse Station, NJ USA), a quadrivalent vaccine containing L1 virus-like particles (VLPs) of types -6, 11, 16, and 18, and Cervarix (GlaxoSmithKline Biologicals, Rixensart, Belgium), a bivalent vaccine containing VLPs of types -16 and 18. In efficacy trials involving young women, both vaccines produced outstanding efficacy against primary and… CONTINUE READING
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