An update of genetic basis of PCOS pathogenesis.

@article{Crespo2018AnUO,
  title={An update of genetic basis of PCOS pathogenesis.},
  author={Raiane P Crespo and Tania A. S. S. Bachega and Berenice Bilharinho de Mendonca and Larissa Garcia Gomes},
  journal={Archives of endocrinology and metabolism},
  year={2018},
  volume={62 3},
  pages={
          352-361
        }
}
Polycystic ovary syndrome (PCOS) is a common and complex endocrine disorder that affects 5-20% of reproductive age women. PCOS clinical symptoms include hirsutism, menstrual dysfunction, infertility, obesity and metabolic syndrome. There is a wide heterogeneity in clinical manifestations and metabolic complications. The pathogenesis of PCOS is not fully elucidated, but four aspects seem to contribute to the syndrome to different degrees: increased ovarian and/or adrenal androgen secretion… 

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