An unusual population of pyramidal neurons in the anterior cingulate cortex of hominids contains the calcium-binding protein calretinin.

@article{Hof2001AnUP,
  title={An unusual population of pyramidal neurons in the anterior cingulate cortex of hominids contains the calcium-binding protein calretinin.},
  author={Patrick R. Hof and Esther A. Nimchinsky and Daniel P. Perl and Joseph M. Erwin},
  journal={Neuroscience letters},
  year={2001},
  volume={307 3},
  pages={139-42}
}
In the context of an on-going comparative analysis of primate neocortex evolution, we describe the occurrence and distribution of a previously unrecognized group of pyramidal neurons, restricted to the superficial part of layer V in the anterior cingulate cortex of hominids and characterized by immunoreactivity to the calcium-binding protein, calretinin. These neurons were rare in orangutans, more numerous in gorillas and common chimpanzees, while humans had the highest numbers. These… CONTINUE READING