An unusual intrinsically disordered protein from the model legume Lotus japonicus stabilizes proteins in vitro.

@article{Haaning2008AnUI,
  title={An unusual intrinsically disordered protein from the model legume Lotus japonicus stabilizes proteins in vitro.},
  author={Svend Haaning and Simona Radutoiu and S\oren V. Hoffmann and Jens Dittmer and Lise Giehm and Daniel E Otzen and Jens Stougaard},
  journal={The Journal of biological chemistry},
  year={2008},
  volume={283 45},
  pages={31142-52}
}
Intrinsic structural disorder is a prevalent feature of proteins with chaperone activity. Using a complementary set of techniques, we have structurally characterized LjIDP1 (intrinsically disordered protein 1) from the model legume Lotus japonicus, and our results provide the first structural characterization of a member of the Lea5 protein family (PF03242). Contrary to in silico predictions, we show that LjIDP1 is intrinsically disordered and probably exists as an ensemble of conformations… CONTINUE READING