An unusual CD56(bright) CD16(low) NK cell subset dominates the early posttransplant period following HLA-matched hematopoietic stem cell transplantation.

@article{Dulphy2008AnUC,
  title={An unusual CD56(bright) CD16(low) NK cell subset dominates the early posttransplant period following HLA-matched hematopoietic stem cell transplantation.},
  author={Nicolas Dulphy and Philippe Haas and Marc Busson and St{\'e}phanie Belhadj and R{\'e}gis Peffault de Latour and Marie Robin and Maryvonnick Carmagnat and Pascale Loiseau and Ryad Tamouza and Catherine Scieux and Claire Rabian and James P Di Santo and Dominique Charron and Anne Janin and Gerard J Soci{\'e} and Antoine Toubert},
  journal={Journal of immunology},
  year={2008},
  volume={181 3},
  pages={2227-37}
}
The expansion of the cytokine-producing CD56(bright) NK cell subset is a main feature of lymphocyte reconstitution after allogeneic hematopoietic stem cell transplantation (HSCT). We investigated phenotypes and functions of CD56(bright) and CD56(dim) NK subsets from 43 HLA-matched non-T cell-depleted HSCT donor-recipient pairs. The early expansion of CD56(bright) NK cells gradually declined in the posttransplant period but still persisted for at least 1 year and was characterized by the… CONTINUE READING