An unusual 500, 000 bases long oscillation of guanine and cytosine content in human chromosome 21


An oscillation with a period of around 500 kb in guanine and cytosine content (GC%) is observed in the DNA sequence of human chromosome 21. This oscillation is localized in the rightmost one-eighth region of the chromosome, from 43.5 Mb to 46.5 Mb. Five cycles of oscillation are observed in this region with six GC-rich peaks and five GC-poor valleys. The GC… (More)
DOI: 10.1016/j.compbiolchem.2004.09.011


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