An unlikely role for the NAT2 genotypes and haplotypes in the oral cancer of south Indians.

@article{Balaji2012AnUR,
  title={An unlikely role for the NAT2 genotypes and haplotypes in the oral cancer of south Indians.},
  author={Lakshmi Balaji and Balaji Singh Krishna and Lakkakula V.K.S. Bhaskar},
  journal={Archives of oral biology},
  year={2012},
  volume={57 5},
  pages={513-8}
}
UNLABELLED The arylamine N-acetyltransferase 2 (NAT2) enzyme detoxifies a wide spectrum of naturally occurring xenobiotics including carcinogens and drugs. Acetylation catalysed by the NAT2 is an important process in metabolic activation of arylamines to electrophilic intermediates that initiate carcinogenesis. Polymorphism in N-acetyltransferase 2 gene was reported to be associated with the susceptibility of various cancers. OBJECTIVE The aim of our study was to determine whether there is… CONTINUE READING