An unexpected wide population variation of the G1733A polymorphism of the androgen receptor gene: data on the Mediterranean region.

@article{Esteban2005AnUW,
  title={An unexpected wide population variation of the G1733A polymorphism of the androgen receptor gene: data on the Mediterranean region.},
  author={Esther M Esteban and Marc Via and Emili Gonz{\'a}lez-P{\'e}rez and Josep Maria Santamaria and Jean Michel Dugoujon and Giuseppe Vona and Nourdin Harich and Francisco Franco Alvarez de Luna and Angelica A. Saetta and N Bissar and Pedro Moral},
  journal={American journal of human biology : the official journal of the Human Biology Council},
  year={2005},
  volume={17 6},
  pages={690-5}
}
The androgen receptor (AR) has been proposed as a candidate gene for several cancers (breast, prostate, uterine endometrium, colon, and esophagus). Ethnicity is considered an associated risk factor for some of these cancers. Several case-control genetic studies have been focused in samples of the main ethnic groups, but little is known about the distribution of risk polymorphisms in current populations with accurate ethnic and/or geographic origins. The A allele of the G1733A polymorphism of… CONTINUE READING