An unbiased metagenomic search for infectious agents using monozygotic twins discordant for chronic fatigue

@inproceedings{Sullivan2010AnUM,
  title={An unbiased metagenomic search for infectious agents using monozygotic twins discordant for chronic fatigue},
  author={Patrick F. Sullivan and Tobias Allander and Fredrik Lysholm and Shan Goh and Bengt Persson and Andreas Jacks and Birgitta Eveng{\aa}rd and Nancy L Pedersen and Bj{\"o}rn Andersson},
  booktitle={BMC Microbiology},
  year={2010}
}
Chronic fatigue syndrome is an idiopathic syndrome widely suspected of having an infectious or immune etiology. We applied an unbiased metagenomic approach to try to identify known or novel infectious agents in the serum of 45 cases with chronic fatigue syndrome or idiopathic chronic fatigue. Controls were the unaffected monozygotic co-twins of cases, and serum samples were obtained at the same place and time. No novel DNA or RNA viral signatures were confidently identified. Four affected twins… CONTINUE READING
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