An ultrasensitive electrogenerated chemiluminescence-based immunoassay for specific detection of Zika virus

@inproceedings{Acharya2016AnUE,
  title={An ultrasensitive electrogenerated chemiluminescence-based immunoassay for specific detection of Zika virus},
  author={Dhiraj Acharya and Pradip Bastola and Linda Le and Amber M Paul and Estefan{\'i}a Guisado Fern{\'a}ndez and Michael S Diamond and Wujian Miao and Fengwei Bai},
  booktitle={Scientific reports},
  year={2016}
}
Zika virus (ZIKV) is a globally emerging mosquito-transmitted flavivirus that can cause severe fetal abnormalities, including microcephaly. As such, highly sensitive, specific, and cost-effective diagnostic methods are urgently needed. Here, we report a novel electrogenerated chemiluminescence (ECL)-based immunoassay for ultrasensitive and specific detection of ZIKV in human biological fluids. We loaded polystyrene beads (PSB) with a large number of ECL labels and conjugated them with anti-ZIKV… CONTINUE READING
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