An ultra-high pressure liquid chromatography-tandem mass spectrometry method for the quantification of teicoplanin in plasma of neonates.

@article{Begou2017AnUP,
  title={An ultra-high pressure liquid chromatography-tandem mass spectrometry method for the quantification of teicoplanin in plasma of neonates.},
  author={Olga Begou and Aggeliki Kontou and Nikolaos Raikos and Kosmas Sarafidis and Emmanuel Roilides and Ioannis N. Papadoyannis and Helen G Gika},
  journal={Journal of chromatography. B, Analytical technologies in the biomedical and life sciences},
  year={2017},
  volume={1047},
  pages={
          215-222
        }
}
The development and validation of an ultra-high pressure liquid chromatography (UHPLC) tandem mass spectrometry (MS/MS) method was performed with the aim to be applied for the quantification of plasma teicoplanin concentrations in neonates. Pharmacokinetic data of teicoplanin in the neonatal population is very limited, therefore, a sensitive and reliable method for the determination of all isoforms of teicoplanin applied in a low volume of sample is of real importance. Teicoplanin main… CONTINUE READING

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