• DOI:10.1016/j.steroids.2009.10.005
Corpus ID: 44363501

An overview on 5α-reductase inhibitors

@article{Aggarwal2010AnOO,
  title={An overview on 5α-reductase inhibitors},
  author={Saurabh Aggarwal and Suresh Thareja and Abhilasha Verma and T. Bhardwaj and M. Kumar},
  journal={Steroids},
  year={2010},
  volume={75},
  pages={109-153}
}

Saurabh Aggarwal, Suresh Thareja, +2 authors M. Kumar

Published 2010

Biology, Medicine

Steroids

Benign prostatic hyperplasia (BPH) is the noncancerous proliferation of the prostate gland associated with benign prostatic obstruction and lower urinary tract symptoms (LUTS) such as frequency, hesitancy, urgency, etc. Its prevalence increases with age affecting around 70% by the age of 70 years. High activity of 5alpha-reductase enzyme in humans results in excessive dihydrotestosterone levels in peripheral tissues and hence suppression of androgen action by 5alpha-reductase inhibitors is a… CONTINUE READING

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