An overview of the use of the monoclonal antibody OKT3 in renal transplantation.

@article{Norman1988AnOO,
  title={An overview of the use of the monoclonal antibody OKT3 in renal transplantation.},
  author={Douglas J. Norman},
  journal={Transplantation proceedings},
  year={1988},
  volume={20 6},
  pages={1248-52}
}
The murine monoclonal anti-T cell antibody, OKT3, has been used during the past 6 years in various clinical transplantation studies. Undoubtedly it has proved to be the most effective and specific immunosuppressive drug widely available for use in organ transplantation. However, because of problems of first-dose symptoms, recurrent rejection, and antibody… CONTINUE READING