An overview of the structures of protein-DNA complexes

  title={An overview of the structures of protein-DNA complexes},
  author={Nicholas M. Luscombe and Susan E Austin and Helen M. Berman and Janet M. Thornton},
  journal={Genome Biology},
  pages={reviews001.1 - reviews001.37}
On the basis of a structural analysis of 240 protein-DNA complexes contained in the Protein Data Bank (PDB), we have classified the DNA-binding proteins involved into eight different structural/functional groups, which are further classified into 54 structural families. Here we present this classification and review the functions, structures and binding interactions of these protein-DNA complexes. 
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