An overview of the regulation of bone remodelling at the cellular level.

@article{Kular2012AnOO,
  title={An overview of the regulation of bone remodelling at the cellular level.},
  author={Jasreen Kular and Jennifer C Tickner and Shek Man Chim and Jiake Xu},
  journal={Clinical biochemistry},
  year={2012},
  volume={45 12},
  pages={863-73}
}
OBJECTIVES To review the current literature on the regulation of bone remodelling at the cellular level. DESIGN AND METHODS The cellular activities of the cells in the basic multicellular unit (BMU) were evaluated. RESULTS Bone remodelling requires an intimate cross-talk between osteoclasts and osteoblasts and is tightly coordinated by regulatory proteins that interact through complex autocrine/paracrine mechanisms. Osteocytes, bone lining cells, osteomacs, and vascular endothelial cells… CONTINUE READING
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