An overview of pharmaceutical cocrystals as intellectual property.

@article{Trask2007AnOO,
  title={An overview of pharmaceutical cocrystals as intellectual property.},
  author={Andrew Vincent Trask},
  journal={Molecular pharmaceutics},
  year={2007},
  volume={4 3},
  pages={
          301-9
        }
}
  • A. V. Trask
  • Published 4 May 2007
  • Materials Science
  • Molecular pharmaceutics
This review article focuses on the interaction among certain scientific, legal, and regulatory aspects of pharmaceutical crystal forms. The article offers an analysis of pharmaceutical cocrystals as patentable inventions by drawing upon recent scientific developments in the field. Several potential commercial advantages of pharmaceutical cocrystals are highlighted, and a number of recent court decisions involving salient issues are summarized. The article provides an outlook on how the… 

The role of cocrystals in pharmaceutical science.

A REVIEW ON ADVANCES IN PHARMACEUTICAL CO-CRYSTAL PREPARATION ROUTES, INTELLECTUAL PROPERTY PERSPECTIVE AND REGULATORY ASPECTS

As in recent years, due to the pervasiveness of poorly soluble APIs that demonstrates poor and erratic bioavailability, pharmaceutical cocrystal’s applicability to tailor the physicochemical

Pharmaceutical Cocrystal Drug Products: An Outlook on Product Development.

The role of co-crystals in pharmaceutical design.

  • J. Steed
  • Materials Science
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  • 2013

Pharmaceutical Cocrystals: Regulatory and Strategic Aspects, Design and Development.

The design, synthesis, strategic aspects and characteristics of cocrystals along perspectives on its regulatory and intellectual property considerations are dealt with.

A Review about Regulatory Status and Recent Patents of Pharmaceutical Co-Crystals

Whether co-crystals fulfil the requirements for the grant of a patent or not and how cocrystals are going to affect the present scenario of pharmaceuticals are highlighted.

Cocrystal engineering of pharmaceutical solids: therapeutic potential and challenges

An overview of pharmaceutical cocrystal production and its potential in reviving problematic properties of drugs in different dosage forms and the challenges and future outlook of its translational development are discussed.

Recent Advances on the Biological Study of Pharmaceutical Cocrystals

Although pharmaceutical cocrystals face some challenges in clarifying the characteristics of metabolism and distribution, revealing potential pharmacological mechanism, and evaluating safety, cocrystal engineering is still considered a green and promising approach to developing valuable new drugs.

Pharmaceutical Co-Crystals: A New Paradigm of Crystal Engineering

A review on pharmaceutical co-crystals, nutraceutical co-crystals and pharmaceutical co-crystal polymorphs depicting their relevance both in academia and pharmaceutical industry because of their

Engineering and manufacturing of pharmaceutical co-crystals: a review of solvent-free manufacturing technologies.

Design and synthesis of pharmaceutical cocrystals have received great interest and significant efforts have been directed towards computational screening, cocrystal manufacturing in a continuous manner and real-time monitoring for quality purposes by using various analytical tools.
...

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